Poor oral health due to periodontal infection may be a key factor for Alzheimer's Disease. What is of concern is that the bacteria Porphyromonas gingivalis is the keystone pathogen in chronic periodontitis. This bacterium releases toxic proteases called gingipains in the brain that cause amyloid buildup and neurodegeneration.
The amyloid buildup may be the brains protective attempt to ward off this chronic bacterial infection. However, as it increases to buildup over time, the nerve transmission in the area of the brain diminishes with the loss of cognitive abilities such as memory, reading, pattern recognition, information processing, sustained attention and responsible behavior. Or, it may be leading into early Alzheimer's.